- Brorson Pynt, a point
- Ikerasassuaq, a marine channel in Qaasuitsup
- Ikerinarmiut, an island in Qaasuitsup
- Ikermiit, an island in Kujalleq
- Ikermiorsuaq, an island in Qaasuitsup
- Ikermiuarsuk, an island in Kujalleq
- Ikermiut, an island in Kujalleq
- Ikersuaq, a fjord in Kujalleq
- Ikertilik, an island in Qaasuitsup
- Ikikinera, a point in Qaasuitsup
- Ikissat Kangerluat, a bay in Kujalleq
- Ikkattut, an island in Kujalleq
- Iliartalik, an island in Kujalleq
- Ilimaussaq, a mountain in Kujalleq
- Ilivertoq, a coast in Qaasuitsup
- Iliviligssuaq, a cape in Qaasuitsup
- Illoqarajuttoq, a mountain in Sermersooq
- Kap Alfred Beauvais, a point
- Kap Ullidtz, a point
- Kap Varbrud, a point
- Loddevig, a cove
- Nordvestre Havnenas, a point
- Osterelv, a stream
- Ostre Havnenas, a point
- P. K. Larsen Pynt, a point
- Skibsso, a lake
- Ulla O, an island
- Uluatsina, a mountain in Kujalleq
- Ulveodde, a point in Sermersooq
- Ulvesletten, a glacier
- Umiammakku Isbra, a glacier in Qaasuitsup
- Umiarfik, a fjord in Qaasuitsup
- Umiarneq, an inlet in Kujalleq
- Umiartorfit, a point in Qaasuitsup
- Umiiviup Kangerlua, a fjord in Qaasuitsup
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- Umivfik, an island in Kujalleq
- Upernaviarssuit, an island in Qaasuitsup
- Upernaviarssuk, a point in Qaasuitsup
- Upernaviarsuk, an island in Qaasuitsup
- Upernavik, an island in Qaasuitsup
- Upernavik Isfjord, a fjord in Qaasuitsup
- Upernavik Isstrom, a glacier in Qaasuitsup
- Upernivik, an island in Kujalleq
- Userigke, an island in Kujalleq
- Ussing Braer, a glacier in Qaasuitsup
- Ussing Isfjord, a fjord in Qaasuitsup
- Ussut, an island in Kujalleq
- Usuit Kugssuat, a stream in Qaasuitsup
- Usuk, an island in Kujalleq
- Utoqqarmiut in Kujalleq
- Utsussat, a cove in Qaasuitsup
- Uttental Sund, a marine channel in Sermersooq
- Uttorsiutit, an island in Kujalleq
- Uttorsiutit Tunuat, a marine channel in Kujalleq
- Uulaaki, an island in Kujalleq
- Uummannaarsuk, an island in Kujalleq
- Uummannai, an island in Kujalleq
- Uummannalik, an island in Kujalleq
- Uummannaq, an island in Sermersooq
- Uummannarsuaq, an island in Kujalleq
- Uunartoq, an island in Kujalleq
- Uunartoq Fjord, a fjord in Kujalleq
- Uviarssakiaq, a stream in Qaasuitsup
- Uvijoq, a mountain in Qaasuitsup
- Uvingassoq, an island in Qaasuitsup
- V. Clausen Fjord, a fjord
- Vandfaldsdalen, a ravine in Sermersooq
- Vandyke Klipper, a mountain
- Vesterelv, a stream
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